The Four Saints of Impossible Causes

(Saint Rita of Cascia, Saint Jude the Apostle, Saint Philomena, Saint Gregory Thaumaturge)

These 4 saints are known especially for their prowess in interceding for impossible, hopeless, and lost causes.
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Prayer to St. Rita of Cascia
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O Holy Patroness of those in need, St. Rita, whose pleadings before thy Divine Lord are almost irresistible, who for thy lavishness in granting favors hast been called the advocate of the hopeless and even of the impossible; St. Rita so humble, so pure, so mortified, so patient and of such compassionate love for thy Crucified Jesus that thou couldst obtain from him whatsoever thou askest, on account of which all confidently have recourse to thee, expecting, if not always relief, at least comfort; be propitious to our petition, showing thy power with God on behalf of the suppliant; be lavish to us as thou hast been in so many wonderful cases, or the greater glory of God, for the spreading of thine own devotion, and for the consolation of those who trust in thee.
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We promise, if our petition is granted, to glorify, thee by making known thy favor, to bless and sing thy praises forever. Relying upon thy merits and power before the Sacred Heart of Jesus,
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We pray: (mention your request) 
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By thy perfect union with the Divine Will, 
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By the heroic sufferings during thy married life, 
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By the consolation thou didst experience at the conversion of thy husband, 
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By the sacrifice of thy children rather than see them grievously offend God, 
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By thy miraculous entrance into the convent, 
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By thy severe penances and thrice daily bloody scourgings, 
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By the suffering caused by the wound thou didst receive from the thorn of thy crucified Savior, 
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By the divine love which consumed thy heart, 
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By that remarkable devotion to the Blessed Sacrament, on which alone thou didst exist for four years, 
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By the happiness with which thou didst part from thy trials to join thy Divine Spouse, 
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By the perfect example thou gavest to people of every state of life. 
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Pray for us, O holy St. Rita, that we may be made worthy of the promises of Christ.
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Prayer to Saint Jude Patron of Hopeless Cases
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Oh glorious apostle St. Jude, faithful servant and friend of Jesus, the name of the traitor who delivered thy beloved Master into the hands of His enemies has caused thee to be forgotten by many, but the Church honors and invokes thee universally as the patron of hopeless cases–of things despaired of. Pray for me who am so miserable; make use, I implore thee, of that particular privilege accorded thee of bringing visible and speedy help where help is almost despaired of. Come to my assistance in this great need, that I may receive the consolations and succor of heaven in all my necessities, tribulations and sufferings, particularly (mention your request), and that I may bless God with thee and all the elect throughout eternity. I promise thee, O blessed St. Jude, to be ever mindful of this great favor, and I will never cease to honor thee as my special and powerful patron, and to do all in my power to encourage devotion to thee. Amen
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NOVENA PRAYER TO ST. PHILOMENA 1
O FAITHFUL VIRGIN and glorious martyr, St. Philomena, who works so many miracles on behalf of the poor and sorrowing, have pity on me. Thou knowest the multitude and diversity of my needs. Behold me at thy feet, full of misery, but full of hope. I entreat thy charity, O great Saint! Graciously hear me and obtain from God a favorable answer to the request which I now humbly lay before thee. . . 
[Here mention your petition.] I am firmly convinced that through thy merits, through the scorn, the sufferings and the death thou didst endure, united to the merits of the Passion and death of Jesus, thy Spouse, I shall obtain what I ask of thee, and in the joy of my heart I will bless God, who is admirable in His Saints. Amen.
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PRAYER TO ST GREGORY THE WONDERWORKER
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O holy Saint Gregory, confessor and priest of the Lord, I pray thee that thou wouldst intercede with our Lord God for me, that, being purified from all vice, I may please Him in all things, and that He will grant me the peace possessed by all His servants.
Amen.